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C18(plasm)-18:1 PE-d<sub>9</sub>

" in MedChemExpress (MCE) Product Catalog:

98

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4

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10

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1

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11

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11

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27

Isotope-Labeled Compounds

4

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Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-146906S
    C18 Glucosyl(ß) ceramide-d5

    		Isotope-Labeled Compounds Others
    C18 Glucosyl(ß) ceramide-d5 is deuterium labeled C18 Glucosyl(ß) ceramide.
    <em>C18</em> Glucosyl(ß) ceramide-d5
  • HY-130345
    PAF (C18)

    		Platelet-activating Factor Receptor (PAFR) Cardiovascular Disease
    C18-PAF, octadecane PAF, is the ligand of platelet-activating factor and PAF G protein-coupled receptor (PAFR). C18-PAF has renovasodilator properties and antihypertensive lipid properties. C18-PAF increases renal blood flow and causes dose-dependent systemic hypotension .
    PAF (<em>C18</em>)
  • HY-146837S
    C18(plasm)-18:1 PE-d9

    		Isotope-Labeled Compounds Others
    C18(plasm)-18:1 PE-d9 is deuterium labeled C18(plasm)-18:1 PE.
    <em>C18</em>(<em>plasm</em>)-<em>18</em>:1 PE-d9
  • HY-146848S
    C18(plasm)-18:1 PC-d9

    		Isotope-Labeled Compounds Others
    C18(plasm)-18:1 PC-d9 is deuterium labeled C18(plasm)-18:1 PC.
    <em>C18</em>(<em>plasm</em>)-<em>18</em>:1 PC-d9
  • HY-141581
    Lyso-PAF C-18

    		Platelet-activating Factor Receptor (PAFR) Endogenous Metabolite Cardiovascular Disease
    Lyso-PAF C-18 is an intermediate for the synthesis of C18-PAF (HY-130345). It has an easily substituted "Lyso-PAF" structure and is easy to purify and has high yield. C18-PAF is a ligand for platelet-activating factor and PAF G protein-coupled receptor (PAFR) and has renovasodilator properties and antihypertensive lipid properties .
    Lyso-PAF <em>C-18</em>
  • HY-100355S1
    C18-Ceramide-d7

    		Isotope-Labeled Compounds Endogenous Metabolite Others
    C18-Ceramide-d7 is deuterium labeled C18-Ceramide.
    <em>C18</em>-Ceramide-d7
  • HY-100355S
    C18-Ceramide-d3

    		Isotope-Labeled Compounds Others
    C18-Ceramide-d3 is the deuterium labeled C18-Ceramide[1].
    <em>C18</em>-Ceramide-d3
  • HY-130345S
    C18-PAF-d4

    		Isotope-Labeled Compounds Others
    C18-PAF-d4 is the deuterium labeled C18-PAF[1].
    <em>C18</em>-PAF-d4
  • HY-141578S1
    C18:1 Ceramide-d7

    		Isotope-Labeled Compounds Endogenous Metabolite Others
    C18:1 Ceramide-d7 is deuterium labeled C18:1 Ceramide.
    <em>C18</em>:1 Ceramide-d7
  • HY-131701S
    Lactosyl-C18-sphingosine-d7

    		Isotope-Labeled Compounds Others
    Lactosyl-C18-sphingosine-d7 is deuterium labeled Lactosyl-C18-sphingosine.
    Lactosyl-<em>C18</em>-sphingosine-d7
  • HY-141578
    C18:1-Ceramide

    		Endogenous Metabolite Metabolic Disease
    C18:1-Ceramide is a ceramide subspecies. C18:1-Ceramide can be used in the study of type 2 diabetes
    <em>C18</em>:1-Ceramide
  • HY-146907S
    C18:1 Glucosyl ceramide-d5

    		Isotope-Labeled Compounds Others
    C18:1 Glucosyl ceramide-d5 is deuterium labeled C18:1 Glucosyl ceramide.
    <em>C18</em>:1 Glucosyl ceramide-d5
  • HY-100355
    C18-Ceramide

    		Endogenous Metabolite Neurological Disease Cancer
    C18-Ceramide can promote exocytosis of glutamate from damaged neurons. C18-Ceramide promotes cell death in glioma cells. Ceramides is involved in diverse cellular functions, such as differentiation, cell cycle progression, cell-cell adhesion, senescence, and apoptosis .
    <em>C18</em>-Ceramide
  • HY-146876S
    C18:0 GM1 Ganglioside-d5 ammonium

    		Isotope-Labeled Compounds Others
    C18:0 GM1 Ganglioside-d5 (ammonium) is deuterium labeled C18:0 GM1 Ganglioside (ammonium).
    <em>C18</em>:0 GM1 Ganglioside-d5 ammonium
  • HY-141578S
    C18:1-Ceramide-13C18

    		Isotope-Labeled Compounds Others
    C18:1-Ceramide- 13C18 is a 13C-labeled C16-Ceramide[1].
    <em>C18</em>:1-Ceramide-13<em>C18</em>
  • HY-144082
    C18-PEG13-acid

    		PROTAC Linkers Cancer
    C18-PEG13-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
    <em>C18</em>-PEG13-acid
  • HY-157586
    2-Linoleoyl-sn-glycero-3-phosphoethanolamine

    Lysophosphatidylethanolamine C18:2

    		 Others Others
    2-Linoleoyl-sn-glycero-3-phosphoethanolamine (Lysophosphatidylethanolamine C18:2) is a kind of lipid metabolite, that can be used as biomarkers .
    2-Linoleoyl-sn-glycero-3-phosphoethanolamine
  • HY-155663
    GPX4-IN-5

    		Glutathione Peroxidase Ferroptosis Cancer
    GPX4-IN-5 (Compound C18) is a GPX4 covalent inhibitor with an IC50 value of 0.12 μM. GPX4-IN-5 (Compound C18) can induce ferroptosis for the research of triple-negative breast cancer (TNBC) .
    GPX4-IN-5
  • HY-126613
    Laurycolactone A

    		Others Others
    Laurycolactone A is a quassinoid with a C18 basic skeleton. Laurycolactone A can be isolated from Eurycoma longifolia .
    Laurycolactone A
  • HY-W214059S
    N-Acetyl-S-methyl-L-cysteine-d3

    		Isotope-Labeled Compounds Others
    N-Acetyl-S-methyl-L-cysteine-d3 is the deuterium labeled C18:1-Ceramide[1].
    N-Acetyl-S-methyl-L-cysteine-d3
  • HY-146026
    Androgen receptor antagonist 3

    		Androgen Receptor Cancer
    Androgen receptor antagonist 3 (Compound C18) is an androgen receptor (AR) antagonist with an IC50 of 2.4 μM. Androgen receptor antagonist 3 shows anticancer activities .
    Androgen receptor antagonist 3
  • HY-117152
    L-threo-Sphingosine

    L-threo-Sphingosine C-18

    		 p38 MAPK Apoptosis Cancer
    L-threo-Sphingosine is a potent MAPK inhibitor. L-threo-Sphingosine induces apoptosis and clear DNA fragmentation. L-threo-Sphingosine shows anticancer effect .
    L-threo-Sphingosine
  • HY-P4146
    Survodutide

    BI 456906

    		 GLP Receptor GCGR Metabolic Disease
    Survodutide (BI 456906) is a potent, selective glucagon receptor/GLP-1 receptor (GCGR/GLP-1R) dual agonist with EC50s of 0.52 nM and 0.33 nM in CHO-K1 cells, respectively. Survodutide, a 29-amino-acid peptide, is a potent acylated peptide containing a C18 fatty acid. Survodutide has robust anti-obesity efficacy achieved by increasing energy expenditure and decreasing food intake .
    Survodutide
  • HY-P4146A
    Survodutide TFA

    BI 456906 TFA

    		 GLP Receptor GCGR Metabolic Disease
    Survodutide (BI 456906) TFA is a potent, selective glucagon receptor/GLP-1 receptor (GCGR/GLP-1R) dual agonist with EC50s of 0.52 nM and 0.33 nM in CHO-K1 cells, respectively. Survodutide TFA, a 29-amino-acid peptide, is a potent acylated peptide containing a C18 fatty acid. Survodutide TFA has robust anti-obesity efficacy achieved by increasing energy expenditure and decreasing food intake .
    Survodutide TFA
  • HY-E70271
    γ-Linolenoyl-CoA

    		Endogenous Metabolite Metabolic Disease
    γ-Linolenoyl-CoA (C18:3(n6)-CoA) is a fatty acyl-CoA that can be used for lipidomics analysis of fatty acid-coenzyme A (FA-CoA) through LCMS/MS .
    γ-Linolenoyl-CoA
  • HY-W127487
    N-Octadecanoyl-L-homoserine lactone

    		Biochemical Assay Reagents Others
    Quorum sensing is a regulatory system used by bacteria to control gene expression in response to increased cell density. This regulatory process manifests itself in a variety of phenotypes, including biofilm formation and virulence factor production. Coordinated gene expression is achieved through the production, release and detection of small diffusible signaling molecules called autoinducers. N-acylated homoserine lactones (AHLs) comprise a class of such autoinducers, each of which generally consists of a fatty acid coupled to a homoserine lactone (HSL). Modulation of bacterial quorum-sensing signaling systems to suppress pathogenesis represents a new approach to antimicrobial research for infectious diseases. AHLs differ in acyl length (C4-C18), C3 substitution (hydrogen, hydroxyl, or oxo group), and the presence or absence of one or more carbon-carbon double bonds in the fatty acid chain. These differences confer signaling specificity through the affinity of the LuxR family of transcriptional regulators. C18-HSL, one of four lipophilic long acyl side chain AHLs produced by the LuxI AHL synthase homolog SinI, is involved in quorum-sensing signaling in strains of Rhizobium meliloti (a nitrogen-fixing bacterial symbiont of the legume M. sativa) . C18-HSL and other hydrophobic AHLs tend to localize in the relatively lipophilic environment of bacterial cells and cannot diffuse freely across the cell membrane. Long-chain N-acyl homoserine lactones can be exported from cells by efflux pumps, or can be transported between communicating cells by extracellular outer membrane vesicles.
    N-Octadecanoyl-L-homoserine lactone
  • HY-141582
    Ceramide 3

    N-Stearoyl phytosphingosine

    		 Biochemical Assay Reagents Others
    C18 Phytoceramide (t18:0/18:0) (Cer(t18:0/18:0)) is a bioactive sphingolipid found in the stratum corneum of Saccharomyces cerevisiae, wheat grain, and mammalian epidermis. Cer(t18:0/18:0) consists of a phytosphingosine backbone amine linked to a C18 fatty acid chain. Cer(t18:0/18:0) has the function of regulating apoptosis, cell differentiation, proliferation of smooth muscle cells and inhibition of mitochondrial respiratory chain. It also suppresses the expression of allergic cytokines IL-4, TNF-α, and transcription factors c-Jun and NF-κB in histone-stimulated mouse skin tissue. Formulations containing cer(t18:0/18:0) have been used as skin protectants in cosmetics as they reduce water loss and prevent epidermal dehydration and irritation.
    Ceramide 3
  • HY-W115818
    Polyoxyethylene Sorbitan Monostearate

    		Biochemical Assay Reagents Others
    Polyoxyethylene Sorbitan Monostearate is an ester of the saturated fatty acid stearic acid (C18:0). Polyoxyethylene Sorbitan Monostearate can be used as an excipient, such as surfactant, emulsifier, solubilizer, wetting agent. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .
    Polyoxyethylene Sorbitan Monostearate
  • HY-146323
    Antitumor agent-58

    		Apoptosis Cancer
    Antitumor agent-58 (Compound C18) is an anti-tumor agent. Antitumor agent-58 effectively inhibits colony formation and cell migration of MGC-803 cells. Antitumor agent-58 induces apoptosis of MGC-803 cells through activation of the p38 and JNK signaling pathways. Antitumor agent-58 induces mitochondrial dysfunction of MGC-803 cells. Antitumor agent-58 effectively inhibits tumor growth of xenograft model bearing MGC-803 cells .
    Antitumor agent-58
  • HY-141581S
    Lyso-PAF C-18-d4

    		Isotope-Labeled Compounds Others
    Lyso-PAF C-18-d4 is the deuterium labeled Lyso-PAF C-18[1].
    Lyso-PAF <em>C-18</em>-d4
  • HY-P5463
    C18G

    		Bacterial Others
    C18G is a biological active peptide. (C18G is a synthetic α-helical peptide derived from human platelet factor IV. This peptide was found to be antibacterial and is active against Salmonella.)
    <em>C18</em>G
  • HY-149028
    Mem-C1C18

    		Fluorescent Dye Others
    Mem-C1C18 is a polarity-sensitive fluorescent probe with excellent plasma membrane anchoring, high brightness and a sensitive response to environmental polarity by altering the fluorescence lifetime. Mem-C1C18 can be used to quantify changes in the polarity of the plasma membrane during iron death .
    Mem-C1<em>C18</em>
  • HY-103447S1
    Zearalenone-13C18

    Mycotoxin F2-13C<sub>18sub>; Toxin F2-13C<sub>18sub>

    		 Isotope-Labeled Compounds Others
    Zearalenone- 13C18 (Mycotoxin F2- 13C18; Toxin F2- 13C18) is the 13C labeled Zearalenone (HY-103447) . Zearalenone is a mycotoxin produced mainly by fungi belonging to the genus Fusarium in foods and feeds. Possess oestrogenic activity in pigs, cattle and sheep, with low acute toxicity. Causes precocious development of mammae and other estrogenic effects in young gilts .
    Zearalenone-13<em>C18</em>
  • HY-W013812S
    Ethyl linoleate-13C18

    Linoleic Acid-13C<sub>18sub> ethyl ester; Mandenol-13C<sub>18sub>

    		 Isotope-Labeled Compounds Cardiovascular Disease
    Ethyl linoleate- 13C18 is the 13C labeled Ethyl linoleate. Ethyl linoleate inhibit the development of atherosclerotic lesions and the expression of inflammatory mediators[1].
    Ethyl linoleate-13<em>C18</em>
  • HY-114773
    N-Undecanoyl-L-homoserine lactone

    		Biochemical Assay Reagents Others
    Quorum sensing is a regulatory system used by bacteria to control gene expression in response to increased cell density. This regulatory process manifests itself in a variety of phenotypes, including biofilm formation and virulence factor production. Coordinated gene expression is achieved through the production, release and detection of small diffusible signaling molecules called autoinducers. N-acylated homoserine lactones (AHLs) comprise a class of such autoinducers, each of which generally consists of a fatty acid coupled to a homoserine lactone (HSL). Modulation of bacterial quorum-sensing signaling systems to suppress pathogenesis represents a new approach to antimicrobial research for infectious diseases. AHLs differ in acyl length (C4-C18), C3 substitution (hydrogen, hydroxyl, or oxo group), and the presence or absence of one or more carbon-carbon double bonds in the fatty acid chain. These differences confer signaling specificity through the affinity of the LuxR family of transcriptional regulators. C11-HSL has a rare odd-numbered acyl carbon chain and may be a minor quorum-sensing signaling molecule in Pseudomonas aeruginosa strains.
    N-Undecanoyl-L-homoserine lactone
  • HY-RS03457
    CYP2C18 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    CYP2C18 Human Pre-designed siRNA Set A contains three designed siRNAs for CYP2C18 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    CYP2C18 Human Pre-designed siRNA Set A
    CYP2C18 Human Pre-designed siRNA Set A
  • HY-RS01702
    C18orf25 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    C18orf25 Human Pre-designed siRNA Set A contains three designed siRNAs for C18orf25 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    C18orf25 Human Pre-designed siRNA Set A
    C18orf25 Human Pre-designed siRNA Set A
  • HY-B2219S2
    Stearic acid-13C18

    		Isotope-Labeled Compounds Endogenous Metabolite Metabolic Disease Cancer
    Stearic acid- 13C18is the 13C-labeled Stearic acid. Stearic acid is a long chain dietary saturated fatty acid which exists in many animal and vegetable fats and oils.
    Stearic acid-13<em>C18</em>
  • HY-N6725S
    Sterigmatocystine-13C18

    		Endogenous Metabolite Apoptosis Antibiotic Bacterial DNA/RNA Synthesis Isotope-Labeled Compounds Cancer
    Sterigmatocystine- 13C18 is 13C labeled 2,6-Dimethoxyphenol (HY-W003972). 2,6-Dimethoxyphenol is a phenolic compound that is extensively used for the measurement of laccase activity .
    Sterigmatocystine-13<em>C18</em>
  • HY-W127393
    N-Nonanoyl-L-homoserine lactone

    		Biochemical Assay Reagents Others
    Quorum sensing is a regulatory system used by bacteria to control gene expression in response to increased cell density. This regulatory process manifests itself in a variety of phenotypes, including biofilm formation and virulence factor production. Coordinated gene expression is achieved through the production, release and detection of small diffusible signaling molecules called autoinducers. N-acylated homoserine lactones (AHLs) comprise a class of such autoinducers, each of which generally consists of a fatty acid coupled to a homoserine lactone (HSL). Modulation of bacterial quorum-sensing signaling systems to suppress pathogenesis represents a new approach to antimicrobial research for infectious diseases. AHLs differ in acyl length (C4-C18), C3 substitution (hydrogen, hydroxyl, or oxo group), and the presence or absence of one or more carbon-carbon double bonds in the fatty acid chain. These differences confer signaling specificity through the affinity of the LuxR family of transcriptional regulators. C9-HSL is a rare odd-numbered acyl carbon chain produced by wild-type Erwinia carotovora strain SCC 3193 grown in nutrient-rich Luria-Bertani broth (LB) medium.
    N-Nonanoyl-L-homoserine lactone
  • HY-N1446S2
    Oleic acid-13C18

    9-cis-Octadecenoic acid-13C<sub>18sub>; 9Z-Octadecenoic acid-13C<sub>18sub>

    		 Na+/K+ ATPase Endogenous Metabolite Apoptosis Metabolic Disease Cancer
    Oleic acid- 13C18 is the 13C labeled Oleic acid. Oleic acid (9-cis-Octadecenoic acid) is an abundant monounsaturated fatty acid[1]. Oleic acid is a Na+/K+ ATPase activator[2].
    Oleic acid-13<em>C18</em>
  • HY-21268S
    Methyl linolenate-13C18

    		Isotope-Labeled Compounds Others
    Methyl linolenate- 13C18 is the 13C labeled Methyl linolenate[1]. Methyl linolenate is a polyunsaturated fattly acid (PUFA). It is used in studies on the mechanisms and prevention of oxidation/peroxidation of unsaturated fatty acids[2][3]. The IC50 is 60 uM[4].
    Methyl linolenate-13<em>C18</em>
  • HY-134423S
    Stearoyl coenzyme A-13C18 lithium

    		Isotope-Labeled Compounds Others
    Stearoyl coenzyme A- 13C18 (lithium) is the 13C labeled Stearoyl coenzyme A lithium[1]. Stearoyl coenzyme A (Stearoyl-CoA) lithium is an active compound that can be used as a substrate for the determination of stearoyl-Coenzyme desaturase in microsomes[2].
    Stearoyl coenzyme A-13<em>C18</em> lithium
  • HY-109591S
    Oleoyl coenzyme A-13C18 lithium

    		Isotope-Labeled Compounds Others
    Oleoyl coenzyme A- 13C18 (lithium) is the 13C labeled Oleoyl Coenzyme A lithium[1]. Oleoyl coenzyme A (Oleoyl-CoA) is a thioester of oleic acid and coenzyme A. Oleoyl coenzyme A has a role as an Escherichia coli metabolite and a mouse metabolite[2][3].
    Oleoyl coenzyme A-13<em>C18</em> lithium
  • HY-N0729S2
    Linoleic acid-13C18

    		Endogenous Metabolite Cardiovascular Disease Metabolic Disease
    Linoleic acid- 13C18 is the 13C labeled Linoleic acid. Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism [1][2].
    Linoleic acid-13<em>C18</em>
  • HY-N0728S3
    α-Linolenic acid-13C18

    		Isotope-Labeled Compounds PI3K Akt Cardiovascular Disease Cancer
    α-Linolenic acid- 13C18 is the 13C labeled α-Linolenic acid. α-Linolenic acid, isolated from seed oils, is an essential fatty acid that cannot be synthesized by humans. α-Linolenic acid can affect the process of thrombotic through the modulation of PI3K/Akt signaling. α-Linolenic acid possess the anti-arrhythmic properties and is related to cardiovascular disease and cancer[1].
    α-Linolenic acid-13<em>C18</em>
  • HY-RS13999
    SUB1 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    SUB1 Human Pre-designed siRNA Set A contains three designed siRNAs for SUB1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    SUB1 Human Pre-designed siRNA Set A
    SUB1 Human Pre-designed siRNA Set A
  • HY-146227
    DNA topoisomerase II inhibitor 1

    		Topoisomerase Apoptosis Cancer
    DNA topoisomerase II inhibitor 1 (compound 8ed) is a potent DNA topoisomerase II inhibitor. DNA topoisomerase II inhibitor 1 shows anti-proliferative activity. DNA topoisomerase II inhibitor 1 induces apoptosis and cell cycle arrest at sub G1 phase .
    DNA topoisomerase II inhibitor 1
  • HY-10844S1
    Pretomanid-d5

    PA-824-d<sub>5sub>; (S)-PA 824-d<sub>5sub>

    		 Antibiotic Bacterial Isotope-Labeled Compounds Infection Cancer
    Pretomanid-d5 is deuterated labeled Pretomanid (HY-10844). Pretomanid (PA-824) is an antibiotic used for the research of multi-drug-resistant tuberculosis affecting the lungs. Pretomanid exhibits a sub-micromolar MIC against M. tuberculosis (MTB). The MIC values of PA-824 against a panel of MTB pan-sensitive and Rifampin mono-resistant clinical isolates range from 0.015 to 0.25 μg/mL.
    Pretomanid-d5
  • HY-120797
    CRT0273750

    		LPL Receptor Cancer
    CRT0273750 is an autotaxin (ATX) inhibitor and modulates LPA levels in plasm (IC50 = 0.014 μM). CRT0273750 can be used in ATX/LPA-dependent models of cancer .
    CRT0273750

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